PTD-DBM Research Reference

Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.

Researched for: Wnt signaling, wound repair, and hair-follicle regeneration

Hair & Skin Research peptide LyophilizedPowder verified

Also known as: Protein transduction domain-Dishevelled binding motif peptide

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Quick Facts

Reference Sizes

10 mg

Components

RRRRRRRRGGGGRKTGHQICKFRKC

Storage

Use lot-specific analytical and stability documentation

Solubility

Form and salt dependent; verify against the analytical certificate

Catalog Description

PTD-DBM is a 25-amino-acid cell-penetrating peptide designed to block the interaction between CXXC5 and Dishevelled, thereby modulating Wnt/beta-catenin signaling. Published wound and hair findings are preclinical.

Catalog descriptions reflect research context only. Not a medical claim or treatment recommendation.

Research Profile

Half-Life

Not established in human pharmacokinetic studies

Onset

Study-dependent; no validated human onset

Administration Routes (Research)

Topical in mouse studies; human route not established

Reported Research Effects

Wnt/beta-catenin pathway modulation
Wound-healing and hair-neogenesis findings in mice
No human clinical efficacy

Reported Research Side Effects

Human safety and interaction data are incomplete; findings from laboratory or animal models do not establish clinical safety.

Data source: Primary literature and authoritative identity records

Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.

Research Protocols Reported in the Literature

100 uM daily [Topical; 11 days in mice; Once daily]Source: mouse wound study PMID 26056233
2 mM daily [Topical; 14 days in young mice; Once daily]Source: mouse hair-neogenesis experiment summarized in PMID 33573472

Research Interactions

Flagged Avoid / Caution Combinations (Research)

Unvalidated combinations

Reflects patterns reported in research/community literature only. Not a safety guarantee, medical advice, or interaction warning for human use.

Research Notes

Cross-reference catalog inclusion confirmed; sales-page dosing was not promoted to a verified protocol without traceable primary evidence.

Supplementary research context only. Not medical advice or a treatment recommendation.

Sources

CXXC5-Dishevelled peptide wound study — PubMed (NIH)
https://pubmed.ncbi.nlm.nih.gov/26056233/

PTD-DBM hair-regeneration review — PubMed (NIH)
https://pubmed.ncbi.nlm.nih.gov/33573472/

PTD-DBM compound record — PubChem (NIH)
https://pubchem.ncbi.nlm.nih.gov/compound/176453931

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Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.