Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.
Researched for: Vendor-neutral scientific reference catalog entry for L-glutathione
Also known as: Glutathione, Reduced glutathione, GSH, Glutathione-SH, gamma-L-glutamyl-L-cysteinylglycine, L-gamma-glutamyl-L-cysteinylglycine, CAS 70-18-8
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L-glutathione, commonly referring to reduced glutathione (GSH), is the tripeptide L-gamma-glutamyl-L-cysteinylglycine. It is classified as a thiol, tripeptide, L-cysteine derivative, antioxidant, cofactor, and human metabolite. GSH functions in redox reactions, supports glutathione peroxidase, glutathione S-transferase, and glyoxalase systems, participates in xenobiotic conjugation, and helps maintain protein thiol homeostasis.
Source review pending. This descriptive profile is shown from the available source material as a best-effort educational reference. It has not passed the full verification bar and is not a dosing instruction, medical claim, or treatment recommendation.
Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.
Neutral reference information from human studies: one pharmacokinetic study administered 2 g/m² intravenously to 10 healthy volunteers and reported a plasma elimination half-life of 14.1 ± 9.2 minutes. A review of oral supplementation literature reported human studies using 250 or 1,000 mg/day for six months, while dermatology studies have evaluated oral regimens including 250 mg once daily, 250 mg twice daily, and 500 mg once daily. These are published study regimens, not generalized dosing recommendations. Oral absorption, systemic availability, and measured effects vary by formulation and study design. No universal catalog reference size was identified as an authoritative scientific fact; commonSizes is therefore left empty.
Supplementary research context only. Not medical advice or a treatment recommendation.
CAS RN 70-18-8; PubChem CID 124886; ChEBI CHEBI:16856; MeSH D005978; molecular formula C10H17N3O6S; average molecular mass 307.328 g/mol; InChIKey RWSXRVCMGQZWBV-WDSKDSINSA-N
The term L-glutathione generally denotes the reduced thiol form, while oxidized glutathione is glutathione disulfide (GSSG). Oral bioavailability and systemic exposure are formulation- and study-dependent. Following intravenous administration in a human pharmacokinetic study, exogenous glutathione was rapidly cleared and converted or redistributed into sulfur-containing metabolites.
Reflects published research. Educational reference — not a recommendation for use.
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Published articles on this site that mention L-glutathione or one of its catalog aliases.
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