Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.
Researched for: Vendor-neutral scientific reference catalog entry for alirocumab
Also known as: Praluent, REGN727, SAR236553, SAR-236553, anti-PCSK9 monoclonal antibody
This entry is a multi-compound blend. Each component can be opened individually in the reconstitution calculator.
Component amounts shown are arithmetic starters based on equal distribution. Edit values in the calculator before saving.
Alirocumab is a recombinant, fully human IgG1 monoclonal antibody directed against PCSK9. It binds PCSK9 and inhibits PCSK9-mediated degradation of hepatic low-density lipoprotein receptors, thereby increasing LDL-receptor availability for clearance of LDL cholesterol. The molecule is produced in Chinese hamster ovary cell suspension culture and has an approximate molecular weight of 146 kDa.
Catalog descriptions reflect research context only. Not a medical claim or treatment recommendation.
Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.
Regulatory product information documents subcutaneous regimens including 75 mg or 150 mg every 2 weeks and 300 mg every 4 weeks in specified clinical contexts. A randomized pharmacokinetic study evaluated a single 75 mg subcutaneous administration using a pre-filled pen at the abdomen, upper arm, or thigh; systemic exposure was similar across injection sites. These regimen and administration details are recorded as neutral study/reference information and are not individualized dosing instructions.
Supplementary research context only. Not medical advice or a treatment recommendation.
UNII: PP0SHH6V16; PubChem CID: 88214187; ATC: C10AX14; EMA product number: EMEA/H/C/003882; FDA BLA: 125559
Alirocumab consists of two disulfide-linked human heavy chains, each linked to a human kappa light chain, with one N-linked glycosylation site in each heavy-chain CH2 domain. It is supplied as a sterile, preservative-free, clear, colorless to pale-yellow solution at approximately pH 6.0.
Reflects published research. Educational reference — not a recommendation for use.
Found a relevant Reddit or forum thread about this compound? Suggest it below. Every suggestion is reviewed by an editor before it appears -- nothing is published automatically.
Published articles on this site that mention alirocumab or one of its catalog aliases.
Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.