Vitamin B1 (Thiamine) Research Reference

Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.

Researched for: PepTools vendor-neutral scientific reference catalog

Water-soluble B vitamin compound Reference needs_revision Best effort · source review pending

Also known as: Thiamine, Thiamin, Aneurine, Antiberiberi factor, Vitamin B1, Vitamin B-1

Best-effort research profile: this record has not passed full two-source scientific verification. Descriptive fields, research protocols, storage/handling notes, and interaction guidance below are shown with their evidence labels, but calculator presets and exact dosing math remain hidden until the record is verified or reaches Community-Supported status.

Quick Facts

Reference Sizes
Not standardized / source review pending
Storage
Storage is form- and preparation-dependent. Thiamine hydrochloride is described as stable in the dry state. An official thiamine hydrochloride injection label specifies storage at 20–25°C, protection from light, and retention in the carton until use.
Solubility
Thiamine hydrochloride: freely soluble in water; soluble in glycerin; slightly soluble in alcohol; insoluble in ether and benzene. Thiamine mononitrate: approximately 1 g dissolves in 35 mL of water and is slightly soluble in alcohol and chloroform.

Best-Effort Research Profile

Thiamine is a vitamin B1 compound that participates in energy metabolism primarily after conversion to thiamine diphosphate, a coenzyme involved in the metabolism of carbohydrates and other alpha-ketoacids. Dietary thiamine is absorbed in the small intestine, and the body stores only limited amounts, primarily in the liver. Reference materials commonly distinguish the parent thiamine entity from salts such as thiamine hydrochloride and thiamine mononitrate.

Source review pending. This descriptive profile is shown from the available source material as a best-effort educational reference. It has not passed the full verification bar and is not a dosing instruction, medical claim, or treatment recommendation.

Research Profile

Administration Routes (Research)
OralIntramuscularSlow intravenous

Reported Research Effects

Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.

Research Notes

This record represents vitamin B1/thiamine as a reference compound and does not imply a single pharmaceutical salt, dosage form, or clinical regimen. Evidence-backed administration information is included only to identify documented pharmaceutical routes. Half-life and onset were left blank because the authoritative sources reviewed did not provide a single generally applicable value for thiamine across forms and routes. CommonSizes was left empty because available strengths vary substantially by salt, dosage form, jurisdiction, and indication; these are formulation facts rather than intrinsic compound properties.

Supplementary research context only. Not medical advice or a treatment recommendation.

Registry Identifiers

PubChem CID 1130; ChEBI CHEBI:18385; CAS 70-16-6 for thiamine; molecular formula C12H17N4OS; thiamine hydrochloride CAS 67-03-8; thiamine hydrochloride molecular formula C12H17ClN4OS·HCl; thiamine hydrochloride molecular weight 337.27 g/mol; InChIKey JZRWCGZRTZMZEH-UHFFFAOYSA-N

Source-Backed Observations

Thiamine is water-soluble and is present in foods, fortified foods, dietary supplements, and pharmaceutical preparations. Most dietary thiamine occurs in phosphorylated forms that are hydrolyzed to free thiamine before absorption. Thiamine hydrochloride is described as freely soluble in water, soluble in glycerin, slightly soluble in alcohol, and insoluble in ether and benzene. Thiamine hydrochloride is rapidly destroyed in neutral or alkaline solutions and is comparatively stable in the dry state.

Reflects published research. Educational reference — not a recommendation for use.

Sources Under Review

Thiamin—Health Professional Fact Sheet
https://ods.od.nih.gov/factsheets/Thiamin-HealthProfessional/ (accessed 2026-09-26)
Thiamine, PubChem Compound Summary, CID 1130
https://pubchem.ncbi.nlm.nih.gov/compound/1130 (accessed 2026-09-26)
thiamine(1+) CHEBI:18385
https://www.ebi.ac.uk/chebi/CHEBI%3A18385 (accessed 2026-09-26)
Thiamine Hydrochloride Injection, USP—Prescribing Information
https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=af3f9344-f743-4bad-b319-53b96e13fee2&version=3 (accessed 2026-09-26)

Suggest a community source

Found a relevant Reddit or forum thread about this compound? Suggest it below. Every suggestion is reviewed by an editor before it appears -- nothing is published automatically.

Related Research Articles

Published articles on this site that mention Vitamin B1 (Thiamine) or one of its catalog aliases.

Related Research Tools

Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.

Scroll to Top