thevetin B Research Reference

Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.

Researched for: Vendor-neutral scientific reference catalog entry for thevetin B

cardenolide cardiac glycoside; gentiobiosylthevetoside; trisaccharide derivative compound Reference needs_revision Best effort · source review pending

Also known as: Thevetin B, Cerberoside

Best-effort research profile: this record has not passed full two-source scientific verification. Descriptive fields, research protocols, storage/handling notes, and interaction guidance below are shown with their evidence labels, but calculator presets and exact dosing math remain hidden until the record is verified or reaches Community-Supported status.

Quick Facts

Reference Sizes
Not standardized / source review pending

Best-Effort Research Profile

Thevetin B is a gentiobiosylthevetoside and trisaccharide derivative of digitoxigenin. Its systematic structure is 3β-[β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-α-L-glucopyranosyloxy]-14-hydroxy-5β-card-20(22)-enolide. It has been identified in plants including Cascabela (Thevetia) peruviana, Thevetia ahouai, and Cerbera manghas.

Source review pending. This descriptive profile is shown from the available source material as a best-effort educational reference. It has not passed the full verification bar and is not a dosing instruction, medical claim, or treatment recommendation.

Research Profile

Reported Research Effects

Data source: Primary literature, regulator records, trial registries, and identity-specific evidence search

Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.

Research Notes

No reliable compound-specific human pharmacokinetic half-life, onset, solubility specification, storage specification, or standardized research reference size was identified in the authoritative sources reviewed. Published work supports analytical isolation and detection, including LC-MS/MS methods for thevetin B in yellow-oleander seed extracts and biological samples. No administration regimen is recorded because the available literature concerns natural-product analysis, pharmacology, and toxicology rather than an established research-use dosing standard.

Supplementary research context only. Not medical advice or a treatment recommendation.

Registry Identifiers

CAS RN: 27127-79-3; PubChem CID: 441850; ChEBI: CHEBI:27511; ChEMBL: CHEMBL263601; KEGG: C08856; UNII: H77H03L5LQ; InChIKey: GZVMBXDQUQRICT-RCGIHWJFSA-N; molecular formula: C42H66O18; average molecular mass: 858.972 g/mol; monoisotopic mass: 858.42492 Da

Source-Backed Observations

Neutral molecular formula C42H66O18 and formal charge 0 are reported by ChEBI and PubChem. The compound is classified within cardenolides and derivatives and is reported as a gentiobiosylthevetoside. Thevetin B has been isolated or analytically detected in Thevetia/Cascabela species and Cerbera manghas. It is a plant-derived cardiac glycoside associated with yellow-oleander toxicology studies.

Reflects published research. Educational reference — not a recommendation for use.

Sources Under Review

Thevetin B | CID 441850
https://pubchem.ncbi.nlm.nih.gov/compound/Thevetin-B (accessed 2026-09-12)
Method validation of a survey of thevetia cardiac glycosides in serum samples
https://pubmed.ncbi.nlm.nih.gov/21376490/ (accessed 2026-09-12)
A review of the natural history, toxinology, diagnosis and clinical management of Nerium oleander and Thevetia peruviana poisoning
https://pubmed.ncbi.nlm.nih.gov/20438743/ (accessed 2026-09-12)
Analytical quantification of the plant specific cardiac glycosides in biological fluids in a rare case of yellow oleander self-poisoning in Italy
https://pubmed.ncbi.nlm.nih.gov/39892858/ (accessed 2026-09-12)

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Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.

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