Testosterone Research Reference

Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.

Researched for: PepTools vendor-neutral scientific reference catalog

Androgenic steroid hormone compound Reference needs_revision Best effort · source review pending

Also known as: trans-testosterone, Virosterone, Homosterone, (17beta)-17-hydroxyandrost-4-en-3-one, delta4-androsten-17beta-ol-3-one

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Best-effort research profile: this record has not passed full two-source scientific verification. Descriptive fields, research protocols, storage/handling notes, and interaction guidance below are shown with their evidence labels, but calculator presets and exact dosing math remain hidden until the record is verified or reaches Community-Supported status.

Quick Facts

Reference Sizes

Not standardized / source review pending

Best-Effort Research Profile

Testosterone is a C19 steroid hormone with androgenic activity. It acts directly through the androgen receptor and can be converted in tissues to dihydrotestosterone or estradiol, which contribute to tissue-specific androgenic and estrogenic effects. Therapeutic testosterone products are available in multiple formulation-dependent routes, including oral, topical, transdermal, buccal, and injectable forms.

Source review pending. This descriptive profile is shown from the available source material as a best-effort educational reference. It has not passed the full verification bar and is not a dosing instruction, medical claim, or treatment recommendation.

Research Profile

Half-Life

Circulating testosterone has a short and variable half-life; authoritative references report approximately 10–100 minutes, while some physiological studies report phase-specific half-lives depending on the measured testosterone fraction and experimental model. Esterified testosterone products have different, substantially longer formulation-specific half-lives.

Administration Routes (Research)

oraltopicaltransdermalbuccalintramuscular injectionsubcutaneous injection

Reported Research Effects

Agonism of the androgen receptor with activation of androgen-responsive gene transcription.
Conversion to dihydrotestosterone by 5-alpha reductase in selected target tissues.
Conversion to estradiol by aromatase, particularly in tissues such as adipose tissue and liver.
Participation in development and maintenance of male reproductive tissues and secondary sex characteristics.
Contribution to skeletal muscle, hair follicle, bone, and other androgen- or estrogen-responsive tissue effects.

Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.

Research Notes

This record describes testosterone as the parent compound rather than a specific pharmaceutical ester or dosage form. FDA-approved testosterone products and their labeling differ by formulation, route, strength, pharmacokinetics, and storage requirements. Evidence-backed product-specific regimens should not be generalized to unesterified testosterone or to other testosterone formulations.

Supplementary research context only. Not medical advice or a treatment recommendation.

Registry Identifiers

CAS RN 58-22-0; PubChem CID 6013; molecular formula C19H28O2; molecular weight 288.4 g/mol; IUPAC name (8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

Source-Backed Observations

The parent testosterone molecule should be distinguished from esterified derivatives such as testosterone cypionate, enanthate, propionate, and undecanoate. Pharmacokinetic properties, dosing intervals, and administration details are formulation-dependent.

Reflects published research. Educational reference — not a recommendation for use.

Sources Under Review

Testosterone | C19H28O2 | CID 6013
https://pubchem.ncbi.nlm.nih.gov/compound/6013 (accessed 2026-09-03)

Definition of therapeutic testosterone
https://www.cancer.gov/publications/dictionaries/cancer-drug/def/therapeutic-testosterone (accessed 2026-09-03)

Testosterone Information
https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/testosterone-information (accessed 2026-09-03)

FDA issues class-wide labeling changes for testosterone products
https://www.fda.gov/drugs/drug-alerts-and-statements/fda-issues-class-wide-labeling-changes-testosterone-products (accessed 2026-09-03)

Androgen Physiology, Pharmacology, Use and Misuse
https://www.ncbi.nlm.nih.gov/books/NBK279000/ (accessed 2026-09-03)

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Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.