Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.
Researched for: Syn-Ake evidence and protocol review
Also known as: Dipeptide diaminobutyroyl benzylamide diacetate
Syn-Ake (dipeptide diaminobutyroyl benzylamide diacetate) is a synthetic tripeptide designed to mimic waglerin-1, a component of Temple Viper venom that causes localized muscle paralysis in prey. It antagonizes the nicotinic acetylcholine receptor (nAChR) on the muscle-cell membrane, reducing its response to acetylcholine - a related but mechanistically distinct approach from the SNARE-complex inhibitors (Argireline/SNAP-8). A 4% topical solution has been reported to reduce forehead wrinkle depth by 52% over 28 days in cosmetic testing.
Catalog descriptions reflect research context only. Not a medical claim or treatment recommendation.
Data source: Primary literature, regulator records, trial registries, and identity-specific evidence search
Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.
Raw-ingredient percentages are not direct-use instructions. Carrier, purity, preservative system, finished-product concentration, and independent clinical evidence must be distinguished.
Supplementary research context only. Not medical advice or a treatment recommendation.
Best-effort summary of forum/Reddit discussion. This is anecdotal community commentary, not a scientific source, and does not count toward this record's verification status. Do not treat it as established fact or medical guidance.
Reddit skincare communities discuss Syn-Ake (a synthetic snake-venom-mimicking peptide) favorably, with several users naming it alongside Argireline as a peptide they 'swear by' for reducing expression lines over years of use, and one user rating it as giving better visible skin-regeneration/firming results than copper peptides. Community guides note it hasn't been studied as extensively as Matrixyl or Argireline, and results are generally described as less dramatic. Anecdotal only -- no clinical citation was located during this review.
Multiple commenters name Syn-Ake as one of their most effective peptides ('gave better results... regenerated beautifully', 'two peptides I absolutely swear by are Argireline and Syn-Ake'); community guide notes it's less studied than more established peptides.
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Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.