Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.
Researched for: SS-31 evidence and protocol review
Also known as: Elamipretide, MTP-131, Bendavia
SS-31 (elamipretide) is a cell-permeable peptide that binds reversibly to cardiolipin in the inner mitochondrial membrane, stabilizing membrane structure and supporting electron-transport-chain function. In September 2025 the FDA granted accelerated approval to elamipretide (brand name Forzinity) to improve muscle strength in adult and pediatric patients (>=30kg) with Barth syndrome - an ultra-rare (~150 patients in the US) TAFAZZIN-mutation mitochondrial cardioskeletal disease - making it the first FDA-approved mitochondria-targeted therapeutic. Continued approval is contingent on confirmatory trial results. SS-31/elamipretide has also been studied in Phase II/III trials for heart failure and primary mitochondrial myopathy, giving it far more human clinical-trial data than most research peptides in this catalog.
Catalog descriptions reflect research context only. Not a medical claim or treatment recommendation.
Data source: Primary literature, regulator records, trial registries, and identity-specific evidence search
Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.
SS-31 is elamipretide. The record now includes four distinct tested human regimens and notes mixed efficacy rather than presenting one generic 0.01-0.25 mg/kg/day range.
Supplementary research context only. Not medical advice or a treatment recommendation.
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Published articles on this site that mention SS-31 or one of its catalog aliases.
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Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.