Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.
Researched for: Vendor-neutral scientific reference catalog entry for SM-102
Also known as: Lipid H, LIPID H, 1-octylnonyl 8-[(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino]octanoate, heptadecan-9-yl 8-((2-hydroxyethyl)(6-oxo-6-(undecyloxy)hexyl)amino)octanoate, octanoic acid, 8-[(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino]-, 1-octylnonyl ester
SM-102 is an achiral ionizable lipid with a tertiary amine, ester-containing lipid tails, and a hydroxyethyl headgroup. It is used with other lipids to form lipid nanoparticles for encapsulation and intracellular delivery of mRNA and other nucleic acids. Regulatory and scientific sources identify SM-102 as an ionizable-lipid component of Moderna mRNA vaccine lipid nanoparticles.
Source review pending. This descriptive profile is shown from the available source material as a best-effort educational reference. It has not passed the full verification bar and is not a dosing instruction, medical claim, or treatment recommendation.
Data source: Primary literature, regulator records, trial registries, and identity-specific evidence search
Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.
SM-102 is a formulation excipient or delivery-lipid component rather than an independently characterized therapeutic active ingredient. Reported dose levels, pharmacokinetics, solubility, storage conditions, and administration details are formulation-dependent and were not populated where authoritative sources did not provide compound-specific values. The 2019 primary study evaluated SM-102-containing lipid nanoparticles after intramuscular administration in animal mRNA-vaccine research and also compared formulations after intravenous administration.
Supplementary research context only. Not medical advice or a treatment recommendation.
CAS 2089251-47-6; FDA UNII T7OBQ65G2I; PubChem CID 126697616; EPA CompTox DTXSID301336730; molecular formula C44H87NO5; molecular weight 710.17 g/mol; InChIKey BGNVBNJYBVCBJH-UHFFFAOYSA-N; SMILES CCCCCCCCCCCOC(=O)CCCCCN(CCCCCCCC(=O)OC(CCCCCCCC)CCCCCCCC)CCO
The FDA Global Ingredient Name (GSRS) record lists SM-102 as a validated chemical substance and provides the systematic names, formula, molecular weight, CAS number, UNII, InChIKey, and SMILES. FDA technical material classifies SM-102 among ionizable lipids used in lipid nanoparticle products and reports an apparent pKa of approximately 6.68 in the referenced formulation context. Regulatory product documentation lists SM-102 among the lipid components of Moderna mRNA vaccine formulations.
Reflects published research. Educational reference — not a recommendation for use.
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Published articles on this site that mention SM-102 or one of its catalog aliases.
Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.