Semaglutide sodium Research Reference

Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.

Researched for: PepTools vendor-neutral scientific reference catalog

Peptide; glucagon-like peptide-1 receptor agonist compound Reference needs_revision Best effort · source review pending

Also known as: Semaglutide (sodium salt), Semaglutide sodium salt

Best-effort research profile: this record has not passed full two-source scientific verification. Descriptive fields, research protocols, storage/handling notes, and interaction guidance below are shown with their evidence labels, but calculator presets and exact dosing math remain hidden until the record is verified or reaches Community-Supported status.

Quick Facts

Reference Sizes
Not standardized / source review pending

Best-Effort Research Profile

Semaglutide sodium is represented in PubChem as the sodium salt of semaglutide. The parent semaglutide molecule is a 31-amino-acid modified polypeptide and GLP-1 receptor agonist. PubChem lists the sodium-salt form with molecular formula C187H292N45NaO59 and a computed molecular weight of approximately 4138 g/mol. Regulatory product information for approved semaglutide medicines identifies the active substance as semaglutide rather than semaglutide sodium; the sodium salt form should not be assumed to be equivalent to an approved pharmaceutical formulation.

Source review pending. This descriptive profile is shown from the available source material as a best-effort educational reference. It has not passed the full verification bar and is not a dosing instruction, medical claim, or treatment recommendation.

Research Notes

Do not conflate semaglutide sodium with salcaprozate sodium (SNAC), the separate sodium-containing absorption enhancer used in oral semaglutide formulations. A published patent reports sodium- and phosphate-containing semaglutide compositions and an aqueous solubility result for a particular stabilized composition, but this does not establish a general solubility value for a defined semaglutide sodium salt. Exact stoichiometry, solid-state form, pharmaceutical status, and salt-specific pharmacology remain insufficiently established in authoritative sources.

Supplementary research context only. Not medical advice or a treatment recommendation.

Registry Identifiers

PubChem CID 172871828; molecular formula C187H292N45NaO59; computed molecular weight 4138 g/mol; parent compound PubChem CID 154733530. No separate CAS Registry Number for the sodium-salt record was reliably confirmed.

Source-Backed Observations

PubChem lists Semaglutide (sodium salt) as a distinct compound record created March 20, 2025 and modified August 22, 2026. PubChem also notes that salt forms of semaglutide, including semaglutide sodium and semaglutide acetate, have not been proven safe or effective. Approved regulatory products describe semaglutide as the active substance and separately list sodium-containing excipients or formulation components where applicable.

Reflects published research. Educational reference — not a recommendation for use.

Sources Under Review

Semaglutide (sodium salt), PubChem Compound Summary, CID 172871828
https://pubchem.ncbi.nlm.nih.gov/compound/172871828 (accessed 2026-09-01)
Semaglutide, PubChem Compound Summary, CID 56843331
https://pubchem.ncbi.nlm.nih.gov/compound/Semaglutide (accessed 2026-09-01)
Wegovy, INN-semaglutide, European Public Assessment Report
https://www.ema.europa.eu/en/medicines/human/EPAR/wegovy (accessed 2026-09-01)
Office of Clinical Pharmacology Review: Wegovy (Semaglutide)
https://www.fda.gov/media/166020/download (accessed 2026-09-01)
Improved purification process of semaglutide, WO2022018748A1
https://patents.google.com/patent/WO2022018748A1/en (accessed 2026-09-01)

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Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.

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