Pinealon Research Reference

Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.

Researched for: Pinealon evidence and protocol review

Neuro Research peptide Lyophilized Community-Supported (not scientifically verified)

Also known as: EDR peptide

Community-Supported: unlocked based on forum/Reddit discussion, NOT on peer-reviewed or scientific verification. This content is for research and educational reference only. These compounds, protocols, and dosing figures are not verified, may not be FDA-approved, and are not intended for use in humans or animals. Always independently verify before relying on any of this information.

Quick Facts

Reference Sizes
5 mg, 10 mg
Calculator
Preset available
Storage
Lyophilized: store at -20 deg C. After reconstitution: refrigerate 2-8 deg C; verify beyond-use timing against source COA.
Solubility
Lyophilized; reconstitute in sterile water

Catalog Description

Pinealon (EDR, Glu-Asp-Arg) is a synthetic tripeptide developed by the Khavinson group at the St. Petersburg Institute of Bioregulation and Gerontology, part of a broader class of short bioregulatory peptides the group proposes interact directly with DNA promoter regions via complementary binding to regulatory sequences, modulating gene transcription. It is researched for neuroprotective effects, pineal gland function support, and cognitive enhancement, with particular interest in its blood-brain-barrier penetration given its small size. A peer-reviewed study (MDPI, Pharmaceuticals) examined neuroprotective effects of Khavinson-group tripeptides as epigenetic regulators in a mouse model of Alzheimer's disease - one of the more independently accessible peer-reviewed sources for this compound class, though the broader evidence base remains predominantly Russian-language research.

Catalog descriptions reflect research context only. Not a medical claim or treatment recommendation.

Research Profile

Half-Life
Not well characterized in independent human pharmacokinetic studies
Onset
Multi-day treatment courses used in originating Khavinson-group research protocols
Administration Routes (Research)
SC/IM (per originating research protocols)Intranasal (proposed for BBB-penetration research)

Reported Research Effects

Reported Research Side Effects

Data source: Primary literature, regulator records, trial registries, and identity-specific evidence search

Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.

Research Protocols Reported in the Literature

Research Notes

Most evidence comes from one research tradition; community SC schedules should not be labeled verified.

Supplementary research context only. Not medical advice or a treatment recommendation.

Sources

PubMed literature search: Pinealon peptide clinical trial Khavinson — PubMed (NIH)
https://pubmed.ncbi.nlm.nih.gov/?term=Pinealon%20peptide%20clinical%20trial%20Khavinson

Community Discussion Unverified

Best-effort summary of forum/Reddit discussion. This is anecdotal community commentary, not a scientific source, and does not count toward this record's verification status. Do not treat it as established fact or medical guidance.

Community reports on Pinealon are mixed: some users report noticeable subjective benefits (e.g., at ~2mg over 10 days), while others report no meaningful effect on sleep or recovery. Anecdotal, self-reported, not corroborated by clinical data.

What have your experiences been with pinealon (r/Biohackers)
https://www.reddit.com/r/Biohackers/comments/1hm037v/what_have_your_experiences_been_with_pinealon/

User reports taking about 2mg for 10 days and noticing effects; thread includes other users sharing similar or differing experiences.

Pinealon for sleep – my short experience (no noticeable effect) (r/Biohackers)
https://www.reddit.com/r/Biohackers/comments/1sgojmc/pinealon_for_sleep_my_short_experience_no/

User reports no meaningful impact on sleep or recovery from a short Pinealon trial; a contrasting anecdotal account to more positive reports elsewhere.

Suggest a community source

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Related Research Articles

Published articles on this site that mention Pinealon or one of its catalog aliases.

Related Research Tools

Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.

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