O304 Research Reference

Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.

Researched for: AMPK activation, glucose metabolism, and vascular function

Metabolic Research compound Powder needs_revision Best effort · source review pending

Also known as: ATX-304

Best-effort research profile: this record has not passed full two-source scientific verification. Descriptive fields, research protocols, storage/handling notes, and interaction guidance below are shown with their evidence labels, but calculator presets and exact dosing math remain hidden until the record is verified or reaches Community-Supported status.

Quick Facts

Reference Sizes
Not standardized / source review pending
Storage
Use lot-specific analytical and stability documentation
Solubility
Form and salt dependent; verify against the analytical certificate

Best-Effort Research Profile

O304 (ATX-304) is an investigational pan-AMPK activator. A 28-day exploratory trial in people with type 2 diabetes studied 1,000 mg/day; the primary fasting-plasma-glucose endpoint was not statistically significant, although exploratory secondary signals were reported.

Source review pending. This descriptive profile is shown from the available source material as a best-effort educational reference. It has not passed the full verification bar and is not a dosing instruction, medical claim, or treatment recommendation.

Research Profile

Half-Life
Not established in human pharmacokinetic studies
Onset
Trial endpoints assessed over 28 days
Administration Routes (Research)
Oral

Reported Research Effects

Reported Research Side Effects

Data source: Primary literature and authoritative identity records

Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.

Route-Specific Research Protocols

Amounts and schedules are separated by administration route. Evidence badges distinguish labels, human studies, preclinical work, community reports, and evidence gaps.

Label / guideline Human study Community only Preclinical only Not established
Oral Preclinical only

1000 mg daily

Frequency / timing
Once daily
Duration / setting
28 days
Technique
Oral
Evidence
Preclinical / laboratory study

Context: exploratory type 2 diabetes trial PMID 29925691

Formulation: Oral-mucosal formulations are not dose-equivalent to injectable or topical formulations.

Route safety: Non-human or laboratory exposure. It cannot be converted into a human dose.

Do not convert an amount between routes. Bioavailability, formulation, sterility, monitoring, and clinical context differ by route. Research-use context only; independently verify every cited source.

Research Interactions

Flagged Avoid / Caution Combinations (Research)

Reflects patterns reported in research/community literature only. Not a safety guarantee, medical advice, or interaction warning for human use.

Research Notes

Cross-reference catalog inclusion confirmed; sales-page dosing was not promoted to a verified protocol without traceable primary evidence.

Supplementary research context only. Not medical advice or a treatment recommendation.

Sources Under Review

O304 exploratory type 2 diabetes trial — PubMed Central (NIH)
https://pmc.ncbi.nlm.nih.gov/articles/PMC6124394/
O304 European trial results — EU Clinical Trials Register
https://www.clinicaltrialsregister.eu/ctr-search/trial/2016-002183-13/results

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Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.

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