Methamphetamine Research Reference

Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.

Researched for: Neutral scientific reference catalog record for PepTools; reviewed 2026-09-15.

Central nervous system stimulant; amphetamine-class sympathomimetic; U.S. Schedule II controlled substance compound Reference verified

Also known as: Metamfetamine, Metamphetamine, D-Deoxyephedrine, D-Desoxyephedrine

Quick Facts

Reference Sizes
5 mg tablet
Components
Methamphetamine free base + Methamphetamine hydrochloride
Storage
For the FDA-labeled methamphetamine hydrochloride tablet product: store below 30°C (86°F) in a USP tight, light-resistant container.

Blend Components

This entry is a multi-compound blend. Each component can be opened individually in the reconstitution calculator.

Component
Methamphetamine free base
Calculator Profile
Component
Methamphetamine hydrochloride
Calculator Profile
Open All in Blend Calculator

Component amounts shown are arithmetic starters based on equal distribution. Edit values in the calculator before saving.

Catalog Description

Methamphetamine is a secondary amine related to amphetamine and exists as stereoisomeric free-base and salt forms. The S-enantiomer is described as (2S)-N-methyl-1-phenylpropan-2-amine, with molecular formula C10H15N and molecular weight 149.23 g/mol. Pharmacologically, it produces central nervous system stimulation and increased sympathetic activity. Methamphetamine hydrochloride tablets are an FDA-labeled oral prescription formulation, while nonmedical forms may appear as powders, tablets, or crystalline material.

Catalog descriptions reflect research context only. Not a medical claim or treatment recommendation.

Research Profile

Half-Life
Reported biological half-life of approximately 4 to 5 hours; elimination is influenced by urinary pH.
Administration Routes (Research)
OralSmokedIntranasalInjection

Reported Research Effects

Data source: Primary literature, regulator records, trial registries, and identity-specific evidence search

Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.

Research Notes

FDA labeling describes rapid gastrointestinal absorption, hepatic metabolism through aromatic hydroxylation, N-dealkylation, and deamination, and primarily urinary excretion. The same labeling identifies methamphetamine hydrochloride tablets containing 5 mg per tablet and lists oral administration. DEA information documents nonmedical exposure routes including smoking, intranasal use, and injection; these routes are recorded here only as neutral reference information and not as instructions. Methamphetamine has a high potential for abuse and dependence, and high exposures are associated with serious cardiovascular, neurologic, and thermoregulatory toxicity.

Supplementary research context only. Not medical advice or a treatment recommendation.

Registry Identifiers

PubChem CID 10836; CAS 537-46-2; molecular formula C10H15N; molecular weight 149.23 g/mol; IUPAC name (2S)-N-methyl-1-phenylpropan-2-amine; InChIKey MYWUZJCMWCOHBA-VIFPVBQESA-N

Source-Backed Observations

The parent free base and methamphetamine hydrochloride are distinct chemical forms. The FDA-labeled prescription product is methamphetamine hydrochloride. Methamphetamine, its salts, isomers, and salts of its isomers are listed as Schedule II controlled substances in the United States. The FDA label used for this record was revised in January 2017 and states that it may not be the latest approved labeling.

Reflects published research. Educational reference — not a recommendation for use.

Sources

Methamphetamine | CID 10836
https://pubchem.ncbi.nlm.nih.gov/compound/methamphetamine (accessed 2026-09-15)
Methamphetamine
https://www.dea.gov/factsheets/methamphetamine (accessed 2026-09-15)
Desoxyn (methamphetamine hydrochloride tablets, USP) Prescribing Information
https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/005378s031lbl.pdf (accessed 2026-09-15)

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Related Research Articles

Published articles on this site that mention Methamphetamine or one of its catalog aliases.

Related Research Tools

Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.

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