Latanoprost Free Acid Research Reference

Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.

Researched for: Latanoprost Free Acid evidence and protocol review

General Compounds compound PowderInvestigational topical solution verified

Also known as: Latanoprost acid

Quick Facts

Reference Sizes
10 mg, 100 mg
Storage
No approved consumer storage standard exists for this presentation; follow the lot-specific COA and validated stability data
Solubility
Water-soluble as sodium salt; ophthalmic solution formulation

Catalog Description

Latanoprost Free Acid is the active metabolite of latanoprost, an FDA-approved prostaglandin analog for glaucoma/ocular hypertension. Separately from its approved ophthalmic indication, latanoprost is studied for hair-growth applications: it binds the prostaglandin F2-alpha receptor on hair-follicle dermal papilla cells, increasing the duration of the anagen (growth) phase and resulting in longer, thicker hair shafts - evidence supports its use for both androgenetic alopecia and eyelash/eyebrow hypotrichosis. A registered pilot proof-of-concept clinical trial (ClinicalTrials.gov) is specifically evaluating the therapeutic potential of topical latanoprost acid in hair loss.

Catalog descriptions reflect research context only. Not a medical claim or treatment recommendation.

Research Profile

Half-Life
Rapidly hydrolyzed to the free acid form (active metabolite) after ophthalmic administration; topical hair-research PK not separately established
Onset
Hair-growth outcomes assessed over weeks to months in relevant research
Administration Routes (Research)
Topical scalp in pilot research

Reported Research Effects

Reported Research Side Effects

Data source: Primary literature, regulator records, trial registries, and identity-specific evidence search

Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.

Research Protocols Reported in the Literature

Research Notes

Latanoprost free acid is the active metabolite of the approved prodrug latanoprost. XALATAN's 0.005% ophthalmic dose cannot be imported to raw free acid; the hair study was a very small pilot.

Supplementary research context only. Not medical advice or a treatment recommendation.

Sources

Topical latanoprost acid pilot hair-loss trial — PubMed (NIH)
https://pubmed.ncbi.nlm.nih.gov/42430069/

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Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.

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