GW501516 Research Reference

Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.

Researched for: PPAR-delta signaling and metabolic endpoints

Metabolic Research compound Powder needs_revision Best effort · source review pending

Also known as: GW1516, Cardarine, Endurobol

Best-effort research profile: this record has not passed full two-source scientific verification. Descriptive fields, research protocols, storage/handling notes, and interaction guidance below are shown with their evidence labels, but calculator presets and exact dosing math remain hidden until the record is verified or reaches Community-Supported status.

Quick Facts

Reference Sizes
Not standardized / source review pending
Storage
Use lot-specific analytical and stability documentation
Solubility
Form and salt dependent; verify against the analytical certificate

Best-Effort Research Profile

GW501516 is an investigational PPAR-delta agonist. Early human trials studied lipid endpoints, but development did not produce an approved medicine. Anti-doping authorities warn against its use, and it is prohibited in sport.

Source review pending. This descriptive profile is shown from the available source material as a best-effort educational reference. It has not passed the full verification bar and is not a dosing instruction, medical claim, or treatment recommendation.

Research Profile

Half-Life
No approved-label pharmacokinetic standard
Onset
Trial endpoints were measured over 2 to 12 weeks
Administration Routes (Research)
Oral

Reported Research Effects

Reported Research Side Effects

Data source: Primary literature and authoritative identity records

Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.

Route-Specific Research Protocols

Amounts and schedules are separated by administration route. Evidence badges distinguish labels, human studies, preclinical work, community reports, and evidence gaps.

Label / guideline Human study Community only Preclinical only Not established
Oral Human study only

2.5 mg, 5 mg, or 10 mg daily

Frequency / timing
Once daily
Duration / setting
12 weeks
Technique
Oral
Evidence
Human study protocol

Context: randomized human trial PMID 22814748

Formulation: Oral-mucosal formulations are not dose-equivalent to injectable or topical formulations.

Route safety: Research-study protocol only; it is not an approved or individualized instruction and should not be extrapolated to another route.

Oral Human study only

10 mg daily

Frequency / timing
Once daily
Duration / setting
2 weeks
Technique
Oral
Evidence
Human study protocol

Context: human metabolic trial PMID 18024853

Formulation: Oral-mucosal formulations are not dose-equivalent to injectable or topical formulations.

Route safety: Research-study protocol only; it is not an approved or individualized instruction and should not be extrapolated to another route.

Do not convert an amount between routes. Bioavailability, formulation, sterility, monitoring, and clinical context differ by route. Research-use context only; independently verify every cited source.

Research Interactions

Flagged Avoid / Caution Combinations (Research)

Reflects patterns reported in research/community literature only. Not a safety guarantee, medical advice, or interaction warning for human use.

Research Notes

Cross-reference catalog inclusion confirmed; sales-page dosing was not promoted to a verified protocol without traceable primary evidence.

Supplementary research context only. Not medical advice or a treatment recommendation.

Sources Under Review

PPAR-delta agonist lipid trial — PubMed (NIH)
https://pubmed.ncbi.nlm.nih.gov/22814748/
GW501516 human metabolic study — PubMed (NIH)
https://pubmed.ncbi.nlm.nih.gov/18024853/
Health warning for GW1516 — U.S. Anti-Doping Agency
https://www.usada.org/spirit-of-sport/education/what-should-athletes-know-gw1516/

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Related Research Articles

Published articles on this site that mention GW501516 or one of its catalog aliases.

Related Research Tools

Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.

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