Follistatin-344 Research Reference

Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.

Researched for: activin and myostatin signaling

Structural Research protein Lyophilized verified

Also known as: FST-344, Follistatin 344

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Quick Facts

Reference Sizes

1 mg

Calculator

Preset available

Storage

Lyophilized: store at -20 deg C. After reconstitution: refrigerate 2-8 deg C; verify beyond-use timing against source COA. Investigational - no human safety data.

Solubility

Lyophilized recombinant protein; reconstitute in sterile PBS or sterile water

Catalog Description

Follistatin-344 is a full-length isoform of the naturally occurring glycoprotein follistatin, which binds and neutralizes myostatin (GDF-8) and other TGF-beta superfamily ligands (including activin A and GDF-11). It is studied preclinically for muscle hypertrophy and myostatin inhibition; unlike engineered ligand traps such as ACE-031/ACE-083, it is the naturally occurring full-length protein form. It remains FDA investigational, not approved for human use.

Catalog descriptions reflect research context only. Not a medical claim or treatment recommendation.

Research Profile

Half-Life

Not established in human injection studies

Onset

Not established in humans

Administration Routes (Research)

SC (research use)

Reported Research Effects

Binds and neutralizes myostatin (GDF-8) and related TGF-beta superfamily ligands
Studied for muscle hypertrophy in preclinical/animal research

Reported Research Side Effects

Human systemic safety is unknown
Broad activin-family binding may affect reproductive vascular and metabolic signaling
Product-identity risk

Data source: Black-market analytical study, protein-biology review, and WADA rules

Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.

Research Protocols Reported in the Literature

No controlled human injection protocol is established for material marketed as follistatin-344 [Not established; Not established; Not established]Source: literature and anti-doping evidence review

Research Interactions

Flagged Avoid / Caution Combinations (Research)

Other myostatin or activin-pathway inhibitors

Reflects patterns reported in research/community literature only. Not a safety guarantee, medical advice, or interaction warning for human use.

Research Notes

The prior 100-300 ug SC schedule was unsupported and removed. FST-344 is a precursor sequence rather than a clinically validated injectable drug; market samples require identity verification.

Supplementary research context only. Not medical advice or a treatment recommendation.

Sources

Detection of black-market follistatin 344 — PubMed (NIH)
https://pubmed.ncbi.nlm.nih.gov/31758732/

Myostatin-pathway therapeutic review — Journal of Clinical Investigation
https://www.jci.org/articles/view/148372

2026 Prohibited List — World Anti-Doping Agency
https://www.wada-ama.org/en/resources/world-anti-doping-program/prohibited-list

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Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.