Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.
Researched for: fibroblast signaling and tissue regeneration
Also known as: Basic fibroblast growth factor, bFGF
FGF-2 (Fibroblast Growth Factor-2, basic FGF) is a 146-amino-acid polypeptide that initiates proliferation of mesoderm- and ectoderm-derived cells, including fibroblasts, endothelial cells, and epithelial cells. A randomized controlled Phase II clinical trial demonstrated FGF-2's efficacy in periodontal tissue regeneration, and it has also been systematically reviewed (alongside EGF) for tympanic-membrane regeneration applications - reflecting a genuine RCT-level evidence base broader than most compounds in the cosmetic-peptide category.
Catalog descriptions reflect research context only. Not a medical claim or treatment recommendation.
Data source: Randomized Phase II local-application study and protein-stability literature
Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.
Amounts and schedules are separated by administration route. Evidence badges distinguish labels, human studies, preclinical work, community reports, and evidence gaps.
0.3% recombinant human FGF-2 gel applied once at surgery
Context: Phase II periodontal trial PMCID PMC2432040
Formulation: Concentration, vehicle, treated area, and product sterility are formulation-specific.
Route safety: Research-study protocol only; it is not an approved or individualized instruction and should not be extrapolated to another route.
No route-specific amount established in the reviewed record.
Context: The catalog identifies this route, but its reviewed sources do not establish a separate amount and schedule for it.
Formulation: Route-specific sterile formulation and professional handling requirements apply; concentration cannot be inferred from an oral or topical product.
Route safety: No route-specific protocol is established. Do not infer an amount from another route, component, or formulation.
No route-specific amount established in the reviewed record.
Context: The catalog identifies this route, but its reviewed sources do not establish a separate amount and schedule for it.
Route safety: Non-human or laboratory exposure. It cannot be converted into a human dose.
Do not convert an amount between routes. Bioavailability, formulation, sterility, monitoring, and clinical context differ by route. Research-use context only; independently verify every cited source.
Reflects patterns reported in research/community literature only. Not a safety guarantee, medical advice, or interaction warning for human use.
Clinical periodontal work used a defined 0.3% gel rather than cosmetic serum or raw lyophilized reagent. Cosmetic 30 mL listings are formulation-specific.
Supplementary research context only. Not medical advice or a treatment recommendation.
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Published articles on this site that mention FGF-2 or one of its catalog aliases.
Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.