enicepatide Research Reference

Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.

Researched for: PepTools vendor-neutral scientific reference catalog

Investigational peptide; dual GLP-1/GIP receptor agonist compound Reference needs_revision Best effort · source review pending

Also known as: CT-388, RO7795068, RG6640

Best-effort research profile: this record has not passed full two-source scientific verification. Descriptive fields, research protocols, storage/handling notes, and interaction guidance below are shown with their evidence labels, but calculator presets and exact dosing math remain hidden until the record is verified or reaches Community-Supported status.

Quick Facts

Reference Sizes
Not standardized / source review pending

Best-Effort Research Profile

Enicepatide is a synthetic, lipidated peptide investigational compound developed as a dual glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist. It was designed to produce cAMP-biased signaling with minimal beta-arrestin recruitment and reduced receptor internalization in experimental systems. Clinical development has evaluated subcutaneous administration in obesity, overweight with weight-related comorbidity, and type 2 diabetes. It is not an approved medicine.

Source review pending. This descriptive profile is shown from the available source material as a best-effort educational reference. It has not passed the full verification bar and is not a dosing instruction, medical claim, or treatment recommendation.

Research Profile

Administration Routes (Research)
subcutaneous

Reported Research Effects

Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.

Research Notes

Research regimens reported in primary sources include phase 1 single subcutaneous doses of 0.5–7.5 mg and four once-weekly subcutaneous doses of 5–12 mg. A phase 2 obesity study evaluated once-weekly subcutaneous dosing with titration schemes reaching 24 mg over 48 weeks. A separate phase 2 study in participants with type 2 diabetes and overweight or obesity evaluated once-weekly subcutaneous administration for 48 weeks, with titration up to 24 mg. These are study regimens reported for scientific reference and are not dosing recommendations.

Supplementary research context only. Not medical advice or a treatment recommendation.

Registry Identifiers

Proposed INN: enicepatide; CAS RN: 2869147-44-2; molecular formula: C226H345FN48O67; development codes: CT-388, RO7795068, RG6640.

Source-Backed Observations

The WHO Proposed INN record classifies enicepatide as a dual GIP and GLP-1 receptor agonist and provides the peptide's chemical description, molecular formula, and CAS Registry Number. ClinicalTrials.gov identifies CT-388, RO7795068, and RG6640 as alternative names for enicepatide. Current sources describe the compound as investigational and in late-stage clinical development.

Reflects published research. Educational reference — not a recommendation for use.

Sources Under Review

WHO Drug Information, Vol. 39, No. 2, 2025: Proposed INN List 133
https://cdn.who.int/media/docs/default-source/international-nonproprietary-names-%28inn%29/pl133.pdf (accessed 2026-10-03)
Effects of CT-388, a once-weekly signaling-biased dual GLP-1/GIP receptor agonist, on weight loss and glycemic control in preclinical models and participants with obesity
https://pubmed.ncbi.nlm.nih.gov/41319798/ (accessed 2026-10-03)
A Study of CT-388 in Otherwise Healthy Overweight and Obese Adults and Patients With Type 2 Diabetes Mellitus: NCT04838405
https://clinicaltrials.gov/study/NCT04838405 (accessed 2026-10-03)
A Study of Enicepatide (CT-388) in Participants With Obesity or Overweight With at Least One Weight-Related Comorbidity: NCT06525935
https://clinicaltrials.gov/study/NCT06525935 (accessed 2026-10-03)

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Related Research Articles

Published articles on this site that mention enicepatide or one of its catalog aliases.

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Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.

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