Diisopropylammonium Dichloroacetate Research Reference

Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.

Researched for: historic glucose and lipid metabolism

General Compounds compound Powder verified

Also known as: DADA, DIPA-DCA

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Quick Facts

Reference Sizes

1 g, 5 g

Storage

Store tightly closed in a cool dry place; follow the analytical supplier certificate

Solubility

Water-soluble ionic salt

Catalog Description

Diisopropylammonium dichloroacetate is a salt historically studied in glucose and lipid metabolism. Evidence is frequently conflated with sodium dichloroacetate even though formulation pharmacokinetics and safety cannot be assumed equivalent. Modern controlled human data for this exact salt are insufficient for a catalog dosing protocol.

Catalog descriptions reflect research context only. Not a medical claim or treatment recommendation.

Research Profile

Half-Life

Not established by modern human PK studies for the exact salt

Onset

Not established by modern controlled human studies for the exact salt

Administration Routes (Research)

Oral and parenteral routes appear in historical literature; no current validated product route is established

Reported Research Effects

Historic metabolic research
Dichloroacetate-related pyruvate-dehydrogenase-kinase inhibition is an extrapolation
Exact-salt human effects poorly characterized

Reported Research Side Effects

Exact-salt safety is poorly characterized
DCA-related literature raises peripheral-neuropathy and cumulative-exposure concerns but cannot be transferred quantitatively

Data source: Historic PubMed record, NIH compound registry, and DCA PK literature used only as context

Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.

Research Protocols Reported in the Literature

No modern evidence-based human protocol is established for the exact diisopropylammonium salt [Not established; Not established; Not established]Source: historical literature only

Research Interactions

Flagged Avoid / Caution Combinations (Research)

Do not extrapolate sodium-dichloroacetate combinations or protocols to this salt

Reflects patterns reported in research/community literature only. Not a safety guarantee, medical advice, or interaction warning for human use.

Research Notes

A human decision is needed on whether this historically sourced record belongs in the active catalog. Current 1 g and 5 g common sizes were not independently verified for the exact salt.

Supplementary research context only. Not medical advice or a treatment recommendation.

Sources

DIPA-DCA and sodium DCA metabolic comparison — PubMed (NIH)
https://pubmed.ncbi.nlm.nih.gov/4244198/

NCATS Inxight Drugs DIPA-DCA record — NIH NCATS
https://drugs.ncats.io/drug/BA6QDP0R4E

Human low-dose dichloroacetate kinetics — PubMed (NIH)
https://pubmed.ncbi.nlm.nih.gov/17101744/

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Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.