deoxycholic acid Research Reference

Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.

Researched for: PepTools vendor-neutral scientific reference catalog

secondary bile acid; steroid; cholic acid; cytolytic agent compound Reference needs_revision Best effort · source review pending

Also known as: desoxycholic acid, choleic acid, dihydroxycholanoic acid, deoxycholate, 3alpha,12alpha-dihydroxy-5beta-cholan-24-oic acid

Best-effort research profile: this record has not passed full two-source scientific verification. Descriptive fields, research protocols, storage/handling notes, and interaction guidance below are shown with their evidence labels, but calculator presets and exact dosing math remain hidden until the record is verified or reaches Community-Supported status.

Quick Facts

Reference Sizes
Not standardized / source review pending
Storage
For the FDA-approved 10 mg/mL KYBELLA solution: store at 20 °C to 25 °C, with permitted excursions between 15 °C and 30 °C. This storage information applies to the labeled formulation, not to neat deoxycholic acid.
Solubility
Reported aqueous solubility for deoxycholic acid is 43.6 mg/L at 20 °C. Solubility values for salts or formulated preparations should not be assumed to represent the free acid.

Best-Effort Research Profile

Deoxycholic acid is a bile acid formed by bacterial conversion of cholate. It is usually conjugated with glycine or taurine, acts as a detergent to solubilize dietary fats for intestinal absorption, and is reabsorbed through enterohepatic circulation. The parent compound is classified as a C24 steroid, dihydroxy-5beta-cholanic acid, and bile acid. In the FDA-approved subcutaneous formulation KYBELLA, deoxycholic acid functions as a cytolytic agent by disrupting cell membranes.

Source review pending. This descriptive profile is shown from the available source material as a best-effort educational reference. It has not passed the full verification bar and is not a dosing instruction, medical claim, or treatment recommendation.

Research Profile

Onset
For the FDA-approved 100 mg subcutaneous KYBELLA treatment, median Tmax was 18 minutes after injection; this pharmacokinetic observation applies to that formulation and regimen, not necessarily to unformulated deoxycholic acid.
Administration Routes (Research)
subcutaneous

Reported Research Effects

Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.

Research Notes

Reference information combines identity and chemical-property records with biological classification and FDA-labeled formulation data. FDA dose, timing, route, and pharmacokinetic details are formulation-specific research/reference data for KYBELLA and should not be generalized to other preparations or uses. Common reference package sizes are not treated as an intrinsic scientific property of the compound and are therefore omitted.

Supplementary research context only. Not medical advice or a treatment recommendation.

Registry Identifiers

CAS RN 83-44-3; molecular formula C24H40O4; molecular weight 392.57 g/mol; PubChem CID 222528; ChEBI CHEBI:28834; HMDB HMDB0000626; FDA UNII 005990WHZZ; InChIKey KXGVEGMKQFWNSR-LLQZFEROSA-N

Source-Backed Observations

Deoxycholic acid is an endogenous bile-acid constituent. Most endogenous deoxycholic acid is sequestered in the enterohepatic circulation. Following subcutaneous administration of the approved 100 mg KYBELLA treatment, plasma concentrations returned to the endogenous range within 24 hours; the FDA label does not provide a conventional terminal half-life.

Reflects published research. Educational reference — not a recommendation for use.

Sources Under Review

Deoxycholic Acid, PubChem Compound Summary, CID 222528
https://pubchem.ncbi.nlm.nih.gov/compound/222528 (accessed 2026-09-25)
Deoxycholic Acid, MeSH Descriptor Data
https://meshb.nlm.nih.gov/record/ui?ui=D003840 (accessed 2026-09-25)
KYBELLA (deoxycholic acid) injection, Prescribing Information, Revision 09/2026
https://www.accessdata.fda.gov/drugsatfda_docs/label/2026/206333s006lbl.pdf (accessed 2026-09-25)

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Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.

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