CX11 Research Reference

Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.

Researched for: PepTools vendor-neutral scientific reference catalog

small-molecule CXCR4 antagonist candidate compound Reference needs_revision Best effort · source review pending

Also known as: CX11, piperidinylethanamine derivative

Best-effort research profile: this record has not passed full two-source scientific verification. Descriptive fields, research protocols, storage/handling notes, and interaction guidance below are shown with their evidence labels, but calculator presets and exact dosing math remain hidden until the record is verified or reaches Community-Supported status.

Quick Facts

Reference Sizes
Not standardized / source review pending

Best-Effort Research Profile

CX11 was one of a group of small molecules identified through computational screening and evaluated as a potential CXCR4 inhibitor. In cell-based assays, CX11 inhibited stromal cell-derived factor 1 alpha–induced calcium mobilization in MOLT-4 cells and inhibited HIV-1 envelope glycoprotein–elicited fusion associated with CXCR4. The published study describes CX11 as a piperidinylethanamine derivative containing the cyclopentylpiperidinylmethylpiperidinylethylamine pharmacophore. The designation is study-specific, and a fully standardized chemical identity is not established here from the authoritative sources reviewed.

Source review pending. This descriptive profile is shown from the available source material as a best-effort educational reference. It has not passed the full verification bar and is not a dosing instruction, medical claim, or treatment recommendation.

Research Profile

Reported Research Effects

Data source: Primary literature, regulator records, trial registries, and identity-specific evidence search

Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.

Research Notes

Reported findings are limited to preclinical in-vitro assays in the cited study. Values are assay-specific and should not be interpreted as clinical pharmacology or human-use guidance. Common reference sizes are not established as an appropriate authoritative catalog fact for this study-designated research compound.

Supplementary research context only. Not medical advice or a treatment recommendation.

Registry Identifiers

PMID 25583709; PMCID PMC4356787; DOI 10.1128/AAC.04654-14

Source-Backed Observations

The reviewed authoritative literature supports CX11 as a research compound designation rather than an approved therapeutic or standardized pharmacopoeial substance. No reliable authoritative data were identified for a CAS Registry Number, InChI, InChIKey, molecular formula, molecular weight, solubility, stability, storage conditions, pharmacokinetics, or half-life.

Reflects published research. Educational reference — not a recommendation for use.

Sources Under Review

Insights into the mechanism of inhibition of CXCR4: identification of piperidinylethanamine analogs as anti-HIV-1 inhibitors
https://pubmed.ncbi.nlm.nih.gov/25583709/ (accessed 2026-09-01)
Insights into the Mechanism of Inhibition of CXCR4: Identification of Piperidinylethanamine Analogs as Anti-HIV-1 Inhibitors
https://pmc.ncbi.nlm.nih.gov/articles/PMC4356787/ (accessed 2026-09-01)

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Related Research Articles

Published articles on this site that mention CX11 or one of its catalog aliases.

Related Research Tools

Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.

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