Bromantane Research Reference

Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.

Researched for: fatigue attention and dopaminergic signaling

Nootropic Compounds compound PowderCapsuleNasalspray verified

Also known as: Ladasten

Quick Facts

Reference Sizes
50 mg capsules, 60 capsules, 1 g powder, 10 g powder, 9 mg/spray community-market nasal product
Storage
Store powder or capsules tightly sealed and dry; follow the nasal-product label for formulated liquid
Solubility
Lipophilic and poorly water-soluble; nasal and oral-liquid products use formulation-specific solvents

Catalog Description

Bromantane, marketed in Russia as Ladasten, is an adamantane-derived actoprotector with stimulant and anxiolytic-like effects in older Russian literature. The largest cited clinical program enrolled 728 patients with asthenic disorders at 50-100 mg/day for 28 days, but reporting and methodology do not match modern registered international trials. Mechanistic claims about dopamine synthesis are predominantly preclinical. Intranasal use is a newer community/vendor practice, not a clinical-trial route.

Catalog descriptions reflect research context only. Not a medical claim or treatment recommendation.

Research Profile

Half-Life
Approximately 11 hours is widely reported in secondary summaries; accessible primary human PK documentation is limited
Onset
About 1.5-2 hours is reported for oral dosing in secondary sources; clinical effects were assessed over days to weeks
Administration Routes (Research)
OralIntranasal

Reported Research Effects

Reported Research Side Effects

Data source: Russian clinical literature and review, current vendors, and labeled community evidence

Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.

Route-Specific Research Protocols

Amounts and schedules are separated by administration route. Evidence badges distinguish labels, human studies, preclinical work, community reports, and evidence gaps.

Label / guideline Human study Community only Preclinical only Not established
Oral Human study only

50-100 mg/day

Frequency / timing
Once daily
Duration / setting
28 days
Technique
Oral
Evidence
Human study protocol

Context: Russian multicenter asthenia program; limited modern trial documentation

Formulation: Oral-mucosal formulations are not dose-equivalent to injectable or topical formulations.

Route safety: Research-study protocol only; it is not an approved or individualized instruction and should not be extrapolated to another route.

Intranasal Community only

9-36 mg/day

Frequency / timing
Once daily
Duration / setting
Variable
Technique
Intranasal
Evidence
Community report

Context: community and vendor-reported only; not a validated clinical protocol

Route safety: Unvalidated community report. Do not convert this amount to another route or treat it as a clinically established protocol.

Source status: No direct community citation is attached to this amount.

Do not convert an amount between routes. Bioavailability, formulation, sterility, monitoring, and clinical context differ by route. Research-use context only; independently verify every cited source.

Research Interactions

Flagged Avoid / Caution Combinations (Research)

Reflects patterns reported in research/community literature only. Not a safety guarantee, medical advice, or interaction warning for human use.

Research Notes

Current retail formats include 50 mg 60-count capsules and bulk powder from 1 g upward. Reddit use clusters around 9 mg-per-spray intranasal products, but that route has no clinical PK or safety trial.

Supplementary research context only. Not medical advice or a treatment recommendation.

Sources

Pharmacology of actoprotectors — PubMed Central (NIH)
https://pmc.ncbi.nlm.nih.gov/articles/PMC3762282/
Effect of adamantylbromphenylamine on immunity and asthenia symptoms — Russian Academy of Medical Sciences journal
https://vestnikramn.spr-journal.ru/jour/article/view/496/ru_RU

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Related Research Tools

Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.

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