AOD-9604 Research Reference

Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.

Researched for: lipid metabolism and obesity pharmacology

Metabolic Research peptide LyophilizedSpray verified

Also known as: AOD9604, HGH Fragment 177-191

Quick Facts

Reference Sizes
5 mg, 10 mg
Calculator
Preset available
Storage
Lyophilized: store at -20 deg C. After reconstitution: refrigerate 2-8 deg C; verify beyond-use timing against source COA.
Solubility
Peptide-formulation dependent; no universal reconstitution solvent or concentration is established in published clinical literature

Catalog Description

AOD-9604 is a synthetic 16-amino-acid fragment of the C-terminal region of human growth hormone (176-191) with a stabilizing N-terminal tyrosine substitution, developed by the original developer in the 1990s. It targets fat cells via beta-3 adrenergic receptor activation, triggering lipolysis while inhibiting lipogenesis, without the growth-promoting effects of full-length HGH. Six randomized, double-blind, placebo-controlled trials were run; a 23-week trial reported 2.8kg weight reduction on 1mg/day versus 0.8kg on placebo, but the compound failed to reach statistical significance in its largest Phase IIb trial, and clinical development was discontinued in 2007.

Catalog descriptions reflect research context only. Not a medical claim or treatment recommendation.

Research Profile

Half-Life
Human terminal half-life is not established in the published trial reports
Onset
Clinical weight outcomes were assessed after 12-24 weeks; no validated acute onset has been established
Administration Routes (Research)
Oral (human clinical trials)SC (community use only)Intranasal spray (commercial research format)

Reported Research Effects

Reported Research Side Effects

Data source: the original developer Phase II/IIb trial history

Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.

Research Protocols Reported in the Literature

Research Notes

AOD means Anti-Obesity Drug. Human development used oral formulations and ended after the largest Phase IIb program did not show adequate efficacy. SC dosing is community folklore rather than a published human protocol. No published combination studies support the prior GLP-1 agonist stacks. Reports of gelling are formulation-quality issues and should be handled only under supplier QC instructions.

Supplementary research context only. Not medical advice or a treatment recommendation.

Sources

Safety and Tolerability of the Hexadecapeptide AOD9604 in Humans — Journal of Endocrinology and Metabolism
https://www.jofem.org/index.php/jofem/article/view/157/194
Effects of Human GH and Its Lipolytic Fragment AOD9604 on Lipid Metabolism Following Chronic Treatment in Obese Mice and Beta-3-AR Knock-Out Mice — Endocrinology
https://academic.oup.com/endo/article/142/12/5182/2988749

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Where to Source AOD-9604

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COA verified

AOD-9604

AOD-9604 5mg AOD-9604 5mg — Full 10-Vial Kit

Hacker Peptides

In stock
COA Batch A2AOD5925
$45.00 $17.53

-61.04%

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Third-party links — not affiliated with this site. Not a recommendation for human use. Research compounds are for laboratory and educational use only.

Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.

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