Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.
Researched for: cholinergic signaling and cognitive performance
Also known as: L-alpha glycerylphosphorylcholine, GPC
Alpha-GPC (choline alphoscerate) is a cholinergic precursor for acetylcholine synthesis that crosses the blood-brain barrier effectively, delivering free choline more rapidly than citicoline and producing faster acetylcholine-related effects. A 2025 systematic review/meta-analysis of 3 RCTs (358 dementia patients) found choline alphoscerate significantly outperformed citicoline on the SCAG clinical assessment scale at end of treatment. A separate randomized, double-blind, placebo-controlled trial demonstrated efficacy and safety of choline alphoscerate for amnestic mild cognitive impairment.
Catalog descriptions reflect research context only. Not a medical claim or treatment recommendation.
Data source: 2025 meta-analysis; RCT in amnestic MCI (PubMed Central)
Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.
Amounts and schedules are separated by administration route. Evidence badges distinguish labels, human studies, preclinical work, community reports, and evidence gaps.
300-1200 mg/day
Context: published cognitive research
Formulation: Oral-mucosal formulations are not dose-equivalent to injectable or topical formulations.
Route safety: Research-study protocol only; it is not an approved or individualized instruction and should not be extrapolated to another route.
1000 mg single dose
Context: published growth-hormone secretagogue research
Formulation: Route-specific sterile formulation and professional handling requirements apply; concentration cannot be inferred from an oral or topical product.
Route safety: Research-study protocol only; it is not an approved or individualized instruction and should not be extrapolated to another route.
1000 mg single dose
Context: published growth-hormone secretagogue research
Formulation: Route-specific sterile formulation and professional handling requirements apply; concentration cannot be inferred from an oral or topical product.
Route safety: Research-study protocol only; it is not an approved or individualized instruction and should not be extrapolated to another route.
Do not convert an amount between routes. Bioavailability, formulation, sterility, monitoring, and clinical context differ by route. Research-use context only; independently verify every cited source.
Typically sold as 300-600 mg capsules.
Supplementary research context only. Not medical advice or a treatment recommendation.
Found a relevant Reddit or forum thread about this compound? Suggest it below. Every suggestion is reviewed by an editor before it appears -- nothing is published automatically.
Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.