AHK-Cu Research Reference

Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.

Researched for: hair follicle and dermal papilla biology

Cosmetic Research peptide PowderCreamSerum verified

Also known as: Copper peptide AHK-Cu

Quick Facts

Reference Sizes
100 mg, 500 mg, 1 g, 30 mL
Storage
Follow the supplier COA and formulation preservative system; stability is formulation-specific
Solubility
Water-soluble copper complex; formulation-specific

Catalog Description

AHK-Cu is the copper complex of the tripeptide Ala-His-Lys. A published ex vivo and in vitro study found increased elongation of cultured human hair follicles and proliferation of dermal papilla cells at picomolar-to-nanomolar concentrations. These laboratory findings do not establish a clinical hair-growth effect or a systemic administration protocol. AHK-Cu has a smaller evidence base than GHK-Cu and is commonly sold in topical cosmetic formulations and as bulk powder.

Catalog descriptions reflect research context only. Not a medical claim or treatment recommendation.

Research Profile

Half-Life
Not well characterized in independent human pharmacokinetic studies
Onset
Effects studied over weeks in relevant hair/skin research protocols
Administration Routes (Research)
Laboratory / preclinicalTopical

Reported Research Effects

Reported Research Side Effects

Data source: Published human hair-follicle ex vivo and dermal papilla-cell in vitro study

Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.

Route-Specific Research Protocols

Amounts and schedules are separated by administration route. Evidence badges distinguish labels, human studies, preclinical work, community reports, and evidence gaps.

Label / guideline Human study Community only Preclinical only Not established
Laboratory / preclinical Preclinical only

10^-12 to 10^-9 M continuous exposure

Frequency / timing
Continuous
Duration / setting
12 days
Technique
Ex vivo
Evidence
Preclinical / laboratory study

Context: published human hair-follicle and dermal papilla-cell study PMID 17703734

Route safety: Non-human or laboratory exposure. It cannot be converted into a human dose.

Laboratory / preclinical Preclinical only

10^-12 to 10^-9 M continuous exposure

Frequency / timing
Continuous
Duration / setting
12 days
Technique
in vitro
Evidence
Preclinical / laboratory study

Context: published human hair-follicle and dermal papilla-cell study PMID 17703734

Route safety: Non-human or laboratory exposure. It cannot be converted into a human dose.

Topical Not established

No route-specific amount established in the reviewed record.

Technique
Topical (commercial cosmetic formulations)
Evidence
Route noted; protocol not established

Context: The catalog identifies this route, but its reviewed sources do not establish a separate amount and schedule for it.

Formulation: Concentration, vehicle, treated area, and product sterility are formulation-specific.

Route safety: No route-specific protocol is established. Do not infer an amount from another route, component, or formulation.

Do not convert an amount between routes. Bioavailability, formulation, sterility, monitoring, and clinical context differ by route. Research-use context only; independently verify every cited source.

Research Notes

No published evidence supports SC administration of AHK-Cu. The protocol now reflects the concentrations used in the published ex vivo and in vitro study rather than a vendor-derived topical percentage.

Supplementary research context only. Not medical advice or a treatment recommendation.

Sources

The effect of tripeptide-copper complex on human hair growth in vitro — PubMed (NIH)
https://pubmed.ncbi.nlm.nih.gov/17703734/
Skin Regenerative and Anti-Cancer Actions of Copper Peptides — Cosmetics (MDPI)
https://www.mdpi.com/2079-9284/5/2/29

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Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.

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