KPV Research Reference

Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.

Researched for: KPV preclinical inflammation evidence

Structural Research peptide LyophilizedCapsuleCream verified

Also known as: Lys-Pro-Val

Quick Facts

Reference Sizes
5 mg, 10 mg, 20 mg
Calculator
Preset available
Storage
Lyophilized: store at -20 deg C. After reconstitution: refrigerate 2-8 deg C; verify beyond-use timing against source COA.
Solubility
Small water-soluble tripeptide; delivery and stability depend on formulation

Catalog Description

KPV (Lys-Pro-Val) is the C-terminal tripeptide fragment of alpha-melanocyte-stimulating hormone (alpha-MSH), studied for anti-inflammatory activity primarily via NF-kB pathway inhibition, independent of classical melanocortin-receptor signaling in some models. It has strong preclinical evidence in colitis/gut-inflammation models and skin-barrier/wound research, and is notable for being transported across the intestinal epithelium intact, making oral delivery a research interest for GI inflammation applications.

Catalog descriptions reflect research context only. Not a medical claim or treatment recommendation.

Research Profile

Half-Life
Not characterized in human pharmacokinetic studies
Onset
Preclinical inflammatory markers are assessed over hours to days
Administration Routes (Research)
Oral and topical delivery in preclinical researchSC use is unapproved community practice

Reported Research Effects

Reported Research Side Effects

Data source: Primary cell and mouse intestinal-inflammation studies

Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.

Research Protocols Reported in the Literature

Research Interactions

Flagged Avoid / Caution Combinations (Research)

Reflects patterns reported in research/community literature only. Not a safety guarantee, medical advice, or interaction warning for human use.

Research Notes

KPV is Lys-Pro-Val, the C-terminal alpha-MSH tripeptide. Evidence includes epithelial-cell and mouse colitis models; the prior SC oral and cream protocols were internal compilations rather than human trials.

Supplementary research context only. Not medical advice or a treatment recommendation.

Sources

PepT1-mediated KPV intestinal study — PubMed (NIH)
https://pubmed.ncbi.nlm.nih.gov/18061177/
KPV murine inflammatory-bowel-disease study — PubMed (NIH)
https://pubmed.ncbi.nlm.nih.gov/18092346/
KPV airway epithelial-cell study — PubMed (NIH)
https://pubmed.ncbi.nlm.nih.gov/22837805/

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Related Research Articles

Published articles on this site that mention KPV or one of its catalog aliases.

Related Research Tools

Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.

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