Epithalon Research Reference

Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.

Researched for: telomere and circadian peptide biology

Longevity Research peptide Lyophilized verified

Also known as: Epitalon, AEDG

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Quick Facts

Reference Sizes

10 mg, 20 mg, 30 mg, 35 mg, 50 mg

Calculator

Preset available

Storage

Lyophilized: store at -20 deg C. After reconstitution: refrigerate 2-8 deg C; verify beyond-use timing against source COA.

Solubility

Water-soluble tetrapeptide but salt and formulation are supplier-specific

Catalog Description

Epitalon or Epithalon is the synthetic tetrapeptide Ala-Glu-Asp-Gly and must be distinguished from Epithalamin which is a pineal polypeptide extract. FDA's 2026 review found inadequate human safety and efficacy evidence for the nominated use. The advisory committee recommendation is nonbinding and is not drug approval.

Catalog descriptions reflect research context only. Not a medical claim or treatment recommendation.

Research Profile

Half-Life

Not established in human PK studies

Onset

Not established in controlled human studies

Administration Routes (Research)

Laboratory model-dependentSC use is community practice rather than a validated clinical protocol

Reported Research Effects

Preclinical telomerase and circadian research
Sparse human evidence
No established longevity effect in humans

Reported Research Side Effects

Human safety is inadequately characterized
Immunogenicity and product-quality risks for unapproved injectable material

Data source: 2026 FDA scientific review plus current market checks

Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.

Research Protocols Reported in the Literature

No independently validated modern human dosing protocol is established for synthetic Epitalon [Not established; Not established; Not established]Source: 2026 FDA briefing review

Research Interactions

Flagged Avoid / Caution Combinations (Research)

Unvalidated peptide combinations marketed for longevity or sleep

Reflects patterns reported in research/community literature only. Not a safety guarantee, medical advice, or interaction warning for human use.

Research Notes

The former 5-10 mg SC schedules were vendor/community conventions and were removed. Current RUO listings commonly include 10-50 mg vials.

Supplementary research context only. Not medical advice or a treatment recommendation.

Sources

FDA briefing document for Epitalon-related substances — U.S. Food and Drug Administration
https://www.fda.gov/media/193342/download

July 2026 PCAC meeting materials — U.S. Food and Drug Administration
https://www.fda.gov/advisory-committees/advisory-committee-calendar/july-23-24-2026-meeting-pharmacy-compounding-advisory-committee-07232026

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Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.