5-Amino-1MQ Research Reference

Catalog classification, reference sizes, lab math links, and source-backed data. Educational use only — not medical advice.

Researched for: adipocyte metabolism and NNMT inhibition

Metabolic Research compound PowderCapsuleLiquid verified

Also known as: 5A1MQ, 5-Amino-1-methylquinolinium

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Quick Facts

Reference Sizes

5 mg, 10 mg, 50 mg, 60 capsules x 50 mg, 5 g

Storage

Stability and post-reconstitution storage are not established in peer-reviewed studies; follow the supplier COA and product label

Solubility

Salt and formulation dependent; peer-reviewed formulation data are limited

Catalog Description

5-Amino-1MQ is a small-molecule inhibitor of NNMT (nicotinamide N-methyltransferase), an enzyme implicated in adipocyte NAD+/methionine metabolism. It is studied in preclinical (rodent/cell) models for reduced adipogenesis, improved metabolic efficiency, and fat-cell reduction, with proposed synergy alongside GLP-1 agonists given its distinct NAD+-metabolism-linked mechanism versus GLP-1 receptor agonism - though this combination has not been tested in controlled human trials as of the latest available research.

Catalog descriptions reflect research context only. Not a medical claim or treatment recommendation.

Research Profile

Half-Life

Not established in human pharmacokinetic studies

Onset

Metabolic effects reported over weeks in preclinical rodent models

Administration Routes (Research)

Oral

Reported Research Effects

NNMT enzyme inhibition - implicated in adipocyte NAD+/methionine metabolism
Reduced adipogenesis and improved metabolic efficiency in preclinical models
Proposed (untested in humans) synergy with GLP-1 agonists

Reported Research Side Effects

No human safety/dosing data available (preclinical evidence base only)

Data source: Preclinical NNMT-inhibitor literature

Reflects preclinical/research literature context only. Not a medical claim, dosing instruction, or treatment recommendation.

Research Protocols Reported in the Literature

50-150 mg daily; community-reported only [Oral; 20-30 days then 1-2 weeks off; Daily]Source: community protocol - no published human dosing study

Research Notes

Current storefronts commonly list 5 mg, 10 mg, and 50 mg research vials plus 60-count 50 mg capsules; bulk 5 g powder also appears. No published pharmacologic interaction or combination study supports the prior NAD+ stack claim.

Supplementary research context only. Not medical advice or a treatment recommendation.

Sources

NNMT inhibitor 5-Amino-1MQ reduces obesity in mice — PubMed (NIH)
https://pubmed.ncbi.nlm.nih.gov/32958596/

Quinoline derived small molecule inhibitors of nicotinamide N-methyltransferase and uses thereof — USPTO Patent
https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/12071409

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Where to Source 5-Amino-1MQ

The following are third-party vendor links for this compound, provided for reference only. Some may be affiliate links, and prices/coupons are entered manually and may not always reflect the vendor's current listing. No affiliation, endorsement, or product claim is implied. Verify price, coupon validity, and product specifications directly on the vendor's site before purchase.

COA verified

5-Amino-1MQ

MG: 5-mg MG: 10-mg 5-Amino-1MQ 10mg — Full 10-Vial Kit 5-Amino-1MQ 5mg — Full 10-Vial Kit

Hacker Peptides

In stock

COA Batch A25AM0925

$50.00 $21.85

-56.3%

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Third-party links — not affiliated with this site. Not a recommendation for human use. Research compounds are for laboratory and educational use only.

Research Use Only. All content is for educational and research reference only. Not medical advice, a treatment recommendation, or guidance on human use. Compounds are not FDA-approved drugs unless specifically noted.